Category-specific integration of homeostatic signals in caudal but not rostral human insula

W. Kyle Simmons; Kristina M. Rapuano; Seth J. Kallman; John E. Ingeholm; Bernard Miller; Stephen J. Gotts; Jason A. Avery; Kevin D. Hall; Alex Martin

doi:10.1038/nn.3535

Category-specific integration of homeostatic signals in caudal but not rostral human insula

W. Kyle Simmons, Kristina M. Rapuano, Seth J. Kallman, John E. Ingeholm, Bernard Miller, Stephen J. Gotts, Jason A. Avery, Kevin D. Hall, Alex Martin

Research output: Contribution to journal › Article › peer-review

77 Scopus citations

Abstract

Prevailing theories hold that the insula is functionally organized along its caudal-to-rostral axis, with posterior regions coding lower-level sensory information and anterior regions coding higher-level stimulus significance relative to the body's homeostatic needs. Contrary to predictions of this model, the response of the taste-sensitive region of the caudal, but not rostral, insula to food images was directly related to the body's homeostatic state as indexed by levels of peripheral glucose.

Original language	English
Pages (from-to)	1551-1552
Number of pages	2
Journal	Nature Neuroscience
Volume	16
Issue number	11
DOIs	https://doi.org/10.1038/nn.3535
State	Published - 1 Nov 2013
Externally published	Yes

Access to Document

10.1038/nn.3535

Cite this

@article{44838572aaa34d76a34d025dddfafb04,

title = "Category-specific integration of homeostatic signals in caudal but not rostral human insula",

abstract = "Prevailing theories hold that the insula is functionally organized along its caudal-to-rostral axis, with posterior regions coding lower-level sensory information and anterior regions coding higher-level stimulus significance relative to the body's homeostatic needs. Contrary to predictions of this model, the response of the taste-sensitive region of the caudal, but not rostral, insula to food images was directly related to the body's homeostatic state as indexed by levels of peripheral glucose.",

author = "Simmons, {W. Kyle} and Rapuano, {Kristina M.} and Kallman, {Seth J.} and Ingeholm, {John E.} and Bernard Miller and Gotts, {Stephen J.} and Avery, {Jason A.} and Hall, {Kevin D.} and Alex Martin",

year = "2013",

month = nov,

day = "1",

doi = "10.1038/nn.3535",

language = "English",

volume = "16",

pages = "1551--1552",

journal = "Nature Neuroscience",

issn = "1097-6256",

publisher = "Nature Publishing Group",

number = "11",

}

TY - JOUR

T1 - Category-specific integration of homeostatic signals in caudal but not rostral human insula

AU - Simmons, W. Kyle

AU - Rapuano, Kristina M.

AU - Kallman, Seth J.

AU - Ingeholm, John E.

AU - Miller, Bernard

AU - Gotts, Stephen J.

AU - Avery, Jason A.

AU - Hall, Kevin D.

AU - Martin, Alex

PY - 2013/11/1

Y1 - 2013/11/1

N2 - Prevailing theories hold that the insula is functionally organized along its caudal-to-rostral axis, with posterior regions coding lower-level sensory information and anterior regions coding higher-level stimulus significance relative to the body's homeostatic needs. Contrary to predictions of this model, the response of the taste-sensitive region of the caudal, but not rostral, insula to food images was directly related to the body's homeostatic state as indexed by levels of peripheral glucose.

AB - Prevailing theories hold that the insula is functionally organized along its caudal-to-rostral axis, with posterior regions coding lower-level sensory information and anterior regions coding higher-level stimulus significance relative to the body's homeostatic needs. Contrary to predictions of this model, the response of the taste-sensitive region of the caudal, but not rostral, insula to food images was directly related to the body's homeostatic state as indexed by levels of peripheral glucose.

UR - http://www.scopus.com/inward/record.url?scp=84886947536&partnerID=8YFLogxK

U2 - 10.1038/nn.3535

DO - 10.1038/nn.3535

M3 - Article

C2 - 24077565

AN - SCOPUS:84886947536

SN - 1097-6256

VL - 16

SP - 1551

EP - 1552

JO - Nature Neuroscience

JF - Nature Neuroscience

IS - 11

ER -

Category-specific integration of homeostatic signals in caudal but not rostral human insula

Abstract

Access to Document

Other files and links

Fingerprint

Cite this