Association of Early-Life Stress with Cytomegalovirus Infection in Adults with Major Depressive Disorder

Bart N. Ford; Robert H. Yolken; Robin L. Aupperle; T. Kent Teague; Michael R. Irwin; Martin P. Paulus; Jonathan Savitz

doi:10.1001/jamapsychiatry.2018.4543

Association of Early-Life Stress with Cytomegalovirus Infection in Adults with Major Depressive Disorder

Bart N. Ford, Robert H. Yolken, Robin L. Aupperle, T. Kent Teague, Michael R. Irwin, Martin P. Paulus, Jonathan Savitz

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	545-547
Number of pages	3
Journal	JAMA Psychiatry
Volume	76
Issue number	5
DOIs	https://doi.org/10.1001/jamapsychiatry.2018.4543
State	Published - May 2019
Externally published	Yes

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10.1001/jamapsychiatry.2018.4543

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@article{546e5ee628824e8b9313bf85d2761170,

title = "Association of Early-Life Stress with Cytomegalovirus Infection in Adults with Major Depressive Disorder",

author = "Ford, {Bart N.} and Yolken, {Robert H.} and Aupperle, {Robin L.} and Teague, {T. Kent} and Irwin, {Michael R.} and Paulus, {Martin P.} and Jonathan Savitz",

note = "Funding Information: Concept and design: Ford, Yolken, Aupperle, Teague, Irwin, Savitz. Acquisition, analysis, or interpretation of data: Ford, Yolken, Aupperle, Teague, Paulus, Savitz. Drafting of the manuscript: Ford, Yolken, Irwin, Paulus, Savitz. Critical revision of the manuscript for important intellectual content: All authors. Statistical analysis: Ford, Yolken, Aupperle, Paulus. Obtained funding: Savitz. Administrative, technical, or material support: Yolken, Teague. Supervision: Irwin, Paulus, Savitz. Conflict of Interest Disclosures: None reported. Funding/Support: This research was supported by the National Institute of Mental Health (grant K23MH108707 to Dr Aupperle and grant R21MH113871 to Dr Savitz); the Laureate Institute for Brain Research, National Institute of General Medical Sciences (grant P20GM121312 to Dr Paulus); and the Brain and Behavior Research Foundation (National Alliance for Research on Schizophrenia & Depression grant YI 23850 to Dr Savitz). Role of the Funder/Sponsor: The funders/sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. Disclaimer: Dr Paulus is Associate Editor of JAMA Psychiatry but was not involved in any of the decisions regarding review of the manuscript or its acceptance. 1. Danese A, J Lewis S. Psychoneuroimmunology of early-life stress: the hidden wounds of childhood trauma? Neuropsychopharmacology. 2017;42(1):99-114. doi:10.1038/npp.2016.198 2. Griffiths P, Baraniak I, Reeves M. The pathogenesis of human cytomegalovirus. J Pathol. 2015;235(2):288-297. doi:10.1002/path.4437 3. Victor TA, Khalsa SS, Simmons WK, et al. Tulsa 1000: a naturalistic study protocol for multilevel assessment and outcome prediction in a large psychiatric sample. BMJ Open. 2018;8(1):e016620.",

year = "2019",

month = may,

doi = "10.1001/jamapsychiatry.2018.4543",

language = "English",

volume = "76",

pages = "545--547",

journal = "JAMA Psychiatry",

issn = "2168-622X",

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T1 - Association of Early-Life Stress with Cytomegalovirus Infection in Adults with Major Depressive Disorder

AU - Ford, Bart N.

AU - Yolken, Robert H.

AU - Aupperle, Robin L.

AU - Teague, T. Kent

AU - Irwin, Michael R.

AU - Paulus, Martin P.

AU - Savitz, Jonathan

N1 - Funding Information: Concept and design: Ford, Yolken, Aupperle, Teague, Irwin, Savitz. Acquisition, analysis, or interpretation of data: Ford, Yolken, Aupperle, Teague, Paulus, Savitz. Drafting of the manuscript: Ford, Yolken, Irwin, Paulus, Savitz. Critical revision of the manuscript for important intellectual content: All authors. Statistical analysis: Ford, Yolken, Aupperle, Paulus. Obtained funding: Savitz. Administrative, technical, or material support: Yolken, Teague. Supervision: Irwin, Paulus, Savitz. Conflict of Interest Disclosures: None reported. Funding/Support: This research was supported by the National Institute of Mental Health (grant K23MH108707 to Dr Aupperle and grant R21MH113871 to Dr Savitz); the Laureate Institute for Brain Research, National Institute of General Medical Sciences (grant P20GM121312 to Dr Paulus); and the Brain and Behavior Research Foundation (National Alliance for Research on Schizophrenia & Depression grant YI 23850 to Dr Savitz). Role of the Funder/Sponsor: The funders/sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. Disclaimer: Dr Paulus is Associate Editor of JAMA Psychiatry but was not involved in any of the decisions regarding review of the manuscript or its acceptance. 1. Danese A, J Lewis S. Psychoneuroimmunology of early-life stress: the hidden wounds of childhood trauma? Neuropsychopharmacology. 2017;42(1):99-114. doi:10.1038/npp.2016.198 2. Griffiths P, Baraniak I, Reeves M. The pathogenesis of human cytomegalovirus. J Pathol. 2015;235(2):288-297. doi:10.1002/path.4437 3. Victor TA, Khalsa SS, Simmons WK, et al. Tulsa 1000: a naturalistic study protocol for multilevel assessment and outcome prediction in a large psychiatric sample. BMJ Open. 2018;8(1):e016620.

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Association of Early-Life Stress with Cytomegalovirus Infection in Adults with Major Depressive Disorder

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