Association between dietary pattern scores and the prevalence of colorectal adenoma considering population subgroups

Alyson Haslam, Sara Wagner Robb, James R. Hébert, Hanwen Huang, Mark H. Ebell

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Aim: The purpose of the current study is to examine the dietary patterns in a diverse cohort of individuals and to see if the identified dietary patterns predict the prevalence of adenoma in a cross-sectional study. Methods: Factor analysis was used to derive both sex- and population subgroup-specific dietary patterns among participants in the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Logistic regression was used to assess associations between identified factor scores and colorectal adenoma (CRA) in sex-specific subgroups. Results: Three diet patterns were observed in this cohort: ‘Fruits and vegetables’, ‘Western’ and ‘Sweet and salty’. Foods that loaded on each factor were similar between the racial subgroups. In men, being in the highest quintile of ‘Western’ dietary scores was associated with higher odds of any (adjusted odds ratio (aOR) = 1.21; 95% confidence interval (CI) = 1.03–1.42), advanced (aOR = 1.32; 95% CI = 1.07–1.63) or multiple (>1; aOR = 1.51; 95% CI = 1.17–1.94) adenoma, compared to those in the lowest quintile. These results were most notably seen in Caucasian men. In women, having a ‘Fruits and vegetable’ score in the highest quintile was associated with lower odds of multiple adenoma (>1; aOR = 0.53; 95% CI = 0.28–1.00). Conclusions: Of the three dietary factors, the ‘Western’ diet pattern was most strongly associated with prevalent CRA in Caucasian men. Further research is needed to examine the association between dietary factor scores and adenomas in the proximal colon, where there are larger racial disparities in prevalence.

Original languageEnglish
Pages (from-to)167-175
Number of pages9
JournalNutrition and Dietetics
Volume75
Issue number2
DOIs
StatePublished - 1 Apr 2018
Externally publishedYes

Fingerprint

Adenoma
Odds Ratio
Confidence Intervals
Population
Vegetables
Fruit
Early Detection of Cancer
Ovarian Neoplasms
Statistical Factor Analysis
Colorectal Neoplasms
Lung Neoplasms
Prostatic Neoplasms
Colon
Cross-Sectional Studies
Logistic Models
Diet
Food
Research

Keywords

  • colorectal adenoma
  • dietary pattern
  • population subgroup
  • Western diet

Cite this

Haslam, Alyson ; Wagner Robb, Sara ; Hébert, James R. ; Huang, Hanwen ; Ebell, Mark H. / Association between dietary pattern scores and the prevalence of colorectal adenoma considering population subgroups. In: Nutrition and Dietetics. 2018 ; Vol. 75, No. 2. pp. 167-175.
@article{9cc1551ec38f44a6a3f576135e90f06f,
title = "Association between dietary pattern scores and the prevalence of colorectal adenoma considering population subgroups",
abstract = "Aim: The purpose of the current study is to examine the dietary patterns in a diverse cohort of individuals and to see if the identified dietary patterns predict the prevalence of adenoma in a cross-sectional study. Methods: Factor analysis was used to derive both sex- and population subgroup-specific dietary patterns among participants in the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Logistic regression was used to assess associations between identified factor scores and colorectal adenoma (CRA) in sex-specific subgroups. Results: Three diet patterns were observed in this cohort: ‘Fruits and vegetables’, ‘Western’ and ‘Sweet and salty’. Foods that loaded on each factor were similar between the racial subgroups. In men, being in the highest quintile of ‘Western’ dietary scores was associated with higher odds of any (adjusted odds ratio (aOR) = 1.21; 95{\%} confidence interval (CI) = 1.03–1.42), advanced (aOR = 1.32; 95{\%} CI = 1.07–1.63) or multiple (>1; aOR = 1.51; 95{\%} CI = 1.17–1.94) adenoma, compared to those in the lowest quintile. These results were most notably seen in Caucasian men. In women, having a ‘Fruits and vegetable’ score in the highest quintile was associated with lower odds of multiple adenoma (>1; aOR = 0.53; 95{\%} CI = 0.28–1.00). Conclusions: Of the three dietary factors, the ‘Western’ diet pattern was most strongly associated with prevalent CRA in Caucasian men. Further research is needed to examine the association between dietary factor scores and adenomas in the proximal colon, where there are larger racial disparities in prevalence.",
keywords = "colorectal adenoma, dietary pattern, population subgroup, Western diet",
author = "Alyson Haslam and {Wagner Robb}, Sara and H{\'e}bert, {James R.} and Hanwen Huang and Ebell, {Mark H.}",
year = "2018",
month = "4",
day = "1",
doi = "10.1111/1747-0080.12400",
language = "English",
volume = "75",
pages = "167--175",
journal = "Nutrition and Dietetics",
issn = "1446-6368",
number = "2",

}

Association between dietary pattern scores and the prevalence of colorectal adenoma considering population subgroups. / Haslam, Alyson; Wagner Robb, Sara; Hébert, James R.; Huang, Hanwen; Ebell, Mark H.

In: Nutrition and Dietetics, Vol. 75, No. 2, 01.04.2018, p. 167-175.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Association between dietary pattern scores and the prevalence of colorectal adenoma considering population subgroups

AU - Haslam, Alyson

AU - Wagner Robb, Sara

AU - Hébert, James R.

AU - Huang, Hanwen

AU - Ebell, Mark H.

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Aim: The purpose of the current study is to examine the dietary patterns in a diverse cohort of individuals and to see if the identified dietary patterns predict the prevalence of adenoma in a cross-sectional study. Methods: Factor analysis was used to derive both sex- and population subgroup-specific dietary patterns among participants in the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Logistic regression was used to assess associations between identified factor scores and colorectal adenoma (CRA) in sex-specific subgroups. Results: Three diet patterns were observed in this cohort: ‘Fruits and vegetables’, ‘Western’ and ‘Sweet and salty’. Foods that loaded on each factor were similar between the racial subgroups. In men, being in the highest quintile of ‘Western’ dietary scores was associated with higher odds of any (adjusted odds ratio (aOR) = 1.21; 95% confidence interval (CI) = 1.03–1.42), advanced (aOR = 1.32; 95% CI = 1.07–1.63) or multiple (>1; aOR = 1.51; 95% CI = 1.17–1.94) adenoma, compared to those in the lowest quintile. These results were most notably seen in Caucasian men. In women, having a ‘Fruits and vegetable’ score in the highest quintile was associated with lower odds of multiple adenoma (>1; aOR = 0.53; 95% CI = 0.28–1.00). Conclusions: Of the three dietary factors, the ‘Western’ diet pattern was most strongly associated with prevalent CRA in Caucasian men. Further research is needed to examine the association between dietary factor scores and adenomas in the proximal colon, where there are larger racial disparities in prevalence.

AB - Aim: The purpose of the current study is to examine the dietary patterns in a diverse cohort of individuals and to see if the identified dietary patterns predict the prevalence of adenoma in a cross-sectional study. Methods: Factor analysis was used to derive both sex- and population subgroup-specific dietary patterns among participants in the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Logistic regression was used to assess associations between identified factor scores and colorectal adenoma (CRA) in sex-specific subgroups. Results: Three diet patterns were observed in this cohort: ‘Fruits and vegetables’, ‘Western’ and ‘Sweet and salty’. Foods that loaded on each factor were similar between the racial subgroups. In men, being in the highest quintile of ‘Western’ dietary scores was associated with higher odds of any (adjusted odds ratio (aOR) = 1.21; 95% confidence interval (CI) = 1.03–1.42), advanced (aOR = 1.32; 95% CI = 1.07–1.63) or multiple (>1; aOR = 1.51; 95% CI = 1.17–1.94) adenoma, compared to those in the lowest quintile. These results were most notably seen in Caucasian men. In women, having a ‘Fruits and vegetable’ score in the highest quintile was associated with lower odds of multiple adenoma (>1; aOR = 0.53; 95% CI = 0.28–1.00). Conclusions: Of the three dietary factors, the ‘Western’ diet pattern was most strongly associated with prevalent CRA in Caucasian men. Further research is needed to examine the association between dietary factor scores and adenomas in the proximal colon, where there are larger racial disparities in prevalence.

KW - colorectal adenoma

KW - dietary pattern

KW - population subgroup

KW - Western diet

UR - http://www.scopus.com/inward/record.url?scp=85039149772&partnerID=8YFLogxK

U2 - 10.1111/1747-0080.12400

DO - 10.1111/1747-0080.12400

M3 - Article

C2 - 29280253

AN - SCOPUS:85039149772

VL - 75

SP - 167

EP - 175

JO - Nutrition and Dietetics

JF - Nutrition and Dietetics

SN - 1446-6368

IS - 2

ER -