@article{6b4dc7cc3c474cb3b45317005b30234f,
title = "Assessing the reporting of harms in systematic reviews focused on platelet-rich plasma therapy: a cross-sectional analysis",
abstract = "Aim: Our objectives are: to evaluate the completeness of harms reporting in systematic reviews (SRs) on platelet-rich plasma therapy; to assess the overall methodological quality of the SR using AMSTAR-2 tool; to assess harms reporting overlap in primary studies between SRs. Materials & methods: The authors searched five database systems for relevant literature on platelet rich plasma therapy. The authors screened and extracted in masked, duplicate fashion. Results: All SRs reported less than 50% completeness in harms reporting. The most frequently reported item was harms being stated in the abstract or title (26/103, 25.2%). AMSTAR-2 assessed 96 SRs as 'critically low', 6 SRs as 'low' and 1 'moderate'. Conclusion: Our study highlights that reporting of harms should become more standardized and transparent.",
keywords = "cell therapy, harms, plasma, platelet-rich plasma, PRP, regeneration, repair, therapy",
author = "Shaelyn Ward and Kade Ezell and Audrey Wise and Morgan Garrett and Brayden Rucker and Drew Lestersmith and Mohammed Emam and Matt Vassar",
note = "Funding Information: M Vassar reports receipt of funding from the National Institute on Drug Abuse, the National Institute on Alcohol Abuse and Alcoholism, the US Office of Research Integrity, Oklahoma Center for Advancement of Science and Technology, and internal grants from Oklahoma State University Center for Health Sciences – all outside of the present work. All other authors have nothing to report. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. Publisher Copyright: {\textcopyright} 2023 Future Medicine Ltd.",
year = "2023",
month = jul,
day = "1",
doi = "10.2217/rme-2023-0058",
language = "English",
volume = "18",
pages = "531--542",
journal = "Regenerative Medicine",
issn = "1746-0751",
publisher = "Future Medicine Ltd.",
number = "7",
}