Assays for identification of Hsp90 inhibitors and biochemical methods for discriminating their mechanism of action

Keyphrases

• Mechanism of Action 100%
• Heat Shock Protein 90 (Hsp90) 100%
• Hsp90 Inhibitor 100%
• Biochemical Methods 100%
• Neurodegenerative Diseases 11%
• Fingerprinting 11%
• Pharmacological Properties 11%
• High-throughput Assay 11%
• In Vitro Assay 11%
• Ligand Binding 11%
• Cancer Treatment 11%
• Inhibitor Binding 11%
• Chaperone Hsp90 11%
• ATPase Cycle 11%
• Client Proteins 11%
• Co-chaperone 11%
• ATP Synthase 11%
• Luciferase 11%
• Confirmatory Assay 11%
• Protein Aggregates 11%
• Inhibiting Effect 11%
• Chemical Library 11%
• Oncogenic Proteins 11%
• Culture Cells 11%
• Client Engagement 11%
• ATP-binding Domain 11%
• Drug Target 11%
• HSP70 Expression 11%
• Denatured Protein 11%
• Action-based 11%

Biochemistry, Genetics and Molecular Biology

• Hsp90 100%
• Hsp90 Inhibitor 100%
• N-Terminus 20%
• ATPase 20%
• Co-Chaperone 20%
• Cell Culture 10%
• C-Terminus 10%
• Ligand Binding 10%
• Conformation 10%
• Adenosine Triphosphate 10%
• Luciferase 10%
• Binding Domain 10%
• Hsp70 10%
• Denatured Protein 10%