TY - JOUR
T1 - Analysis of practices to promote reproducibility and transparency in anaesthesiology research
AU - Okonya, Ochije
AU - Rorah, Drayton
AU - Tritz, Daniel
AU - Umberham, Blake
AU - Wiley, Matt
AU - Vassar, Matt
N1 - Funding Information:
This study was funded through the 2019 Presidential Research Fellowship Mentor ? Mentee Program at Oklahoma State University Center for Health Sciences.
Funding Information:
This study was funded through the 2019 Presidential Research Fellowship Mentor – Mentee Program at Oklahoma State University Center for Health Sciences.
Publisher Copyright:
© 2020 British Journal of Anaesthesia
PY - 2020/11
Y1 - 2020/11
N2 - Introduction: Reliable, high-quality research is essential to the field of anaesthesiology. Reproducibility and transparency have been investigated in the biomedical domain and in the social sciences, with both lacking to provide necessary information to reproduce the study findings. In this study, we investigated 14 indicators of reproducibility in anaesthesiology research. Methods: We used the National Library of Medicine catalogue to search for all anaesthesiology journals that are MEDLINE indexed and provide English texts. PubMed was searched with the list of journals to identify all publications from January 1, 2014 to December 31, 2018. We randomly sampled 450 publications that fit the inclusion criteria for our analysis. Data extraction was then conducted in a blinded, duplicate fashion using a pilot-tested Google form. Results: The PubMed search of these journals identified 171 441 publications, with 28 310 being within the time frame. From the 450 publications sampled, 444 full-text publications were accessible. The majority of publications analysed did not have a statement regarding availability of data (164/188), analysis scripts (187/188), or study materials (160/188). Conclusions: Anaesthesiology research needs to improve indicators of reproducibility and transparency. By making research publicly available and improving accessibility to detailed study components, primary research can be reproduced in subsequent studies and help contribute to the development of new practice guidelines.
AB - Introduction: Reliable, high-quality research is essential to the field of anaesthesiology. Reproducibility and transparency have been investigated in the biomedical domain and in the social sciences, with both lacking to provide necessary information to reproduce the study findings. In this study, we investigated 14 indicators of reproducibility in anaesthesiology research. Methods: We used the National Library of Medicine catalogue to search for all anaesthesiology journals that are MEDLINE indexed and provide English texts. PubMed was searched with the list of journals to identify all publications from January 1, 2014 to December 31, 2018. We randomly sampled 450 publications that fit the inclusion criteria for our analysis. Data extraction was then conducted in a blinded, duplicate fashion using a pilot-tested Google form. Results: The PubMed search of these journals identified 171 441 publications, with 28 310 being within the time frame. From the 450 publications sampled, 444 full-text publications were accessible. The majority of publications analysed did not have a statement regarding availability of data (164/188), analysis scripts (187/188), or study materials (160/188). Conclusions: Anaesthesiology research needs to improve indicators of reproducibility and transparency. By making research publicly available and improving accessibility to detailed study components, primary research can be reproduced in subsequent studies and help contribute to the development of new practice guidelines.
KW - anaesthesiology
KW - evidence-based medicine
KW - reproducibility
KW - research design
KW - statistics
UR - http://www.scopus.com/inward/record.url?scp=85087212258&partnerID=8YFLogxK
U2 - 10.1016/j.bja.2020.03.035
DO - 10.1016/j.bja.2020.03.035
M3 - Review article
C2 - 32611528
AN - SCOPUS:85087212258
SN - 0007-0912
VL - 125
SP - 835
EP - 842
JO - British Journal of Anaesthesia
JF - British Journal of Anaesthesia
IS - 5
ER -