TY - JOUR
T1 - An evaluation of the practice of transparency and reproducibility in addiction medicine literature
AU - Adewumi, Mopileola Tomi
AU - Vo, Nam
AU - Tritz, Daniel
AU - Beaman, Jason
AU - Vassar, Matt
N1 - Publisher Copyright:
© 2020 Elsevier Ltd
PY - 2021/1
Y1 - 2021/1
N2 - Background: Credible research emphasizes transparency, openness, and reproducibility. These characteristics are fundamental to promoting and maintaining research integrity. The aim of this study was to evaluate the current state of reproducibility in the field of addiction science. Design: Cross-sectional design. Measurements: The National Library of Medicine catalog was searched for all journals using the subject terms tag: Substance-Related Disorders [ST]. Journals were then searched via PubMed to identify publications from January 1, 2014, to December 31, 2018; 300 publications were randomly selected from among those identified. A pilot-tested Google form containing reproducibility/transparency characteristics was used for data extraction in a duplicated and blinded fashion by two investigators. Findings: Slightly more than half of the publications were open access (152/300, 50.70%). Few publications had pre-registration (7/244, 2.87%), material availability (2/237, 0.84%), protocol availability (3/244, 1.23%), data availability (28/244, 11.48%), or analysis script availability (2/244, 0.82%). Most publications provided a conflict of interest statement (221/293, 75.43%) and funding sources (268/293, 91.47%). One replication study was reported (1/244, 0.4%). Conclusion: Our study found that current practices that promote transparency and reproducibility are lacking, thus, there is room for improvement. In particular, investigators should pre-register studies prior to commencement. Researchers should also make the materials, data, and analysis script publicly available. Further, individuals should be transparent about funding sources for the project and financial conflicts of interest. Research stakeholders should work together toward improvements on these matters. With such protections, the field of addiction medicine can better disseminate the information necessary to treat patients.
AB - Background: Credible research emphasizes transparency, openness, and reproducibility. These characteristics are fundamental to promoting and maintaining research integrity. The aim of this study was to evaluate the current state of reproducibility in the field of addiction science. Design: Cross-sectional design. Measurements: The National Library of Medicine catalog was searched for all journals using the subject terms tag: Substance-Related Disorders [ST]. Journals were then searched via PubMed to identify publications from January 1, 2014, to December 31, 2018; 300 publications were randomly selected from among those identified. A pilot-tested Google form containing reproducibility/transparency characteristics was used for data extraction in a duplicated and blinded fashion by two investigators. Findings: Slightly more than half of the publications were open access (152/300, 50.70%). Few publications had pre-registration (7/244, 2.87%), material availability (2/237, 0.84%), protocol availability (3/244, 1.23%), data availability (28/244, 11.48%), or analysis script availability (2/244, 0.82%). Most publications provided a conflict of interest statement (221/293, 75.43%) and funding sources (268/293, 91.47%). One replication study was reported (1/244, 0.4%). Conclusion: Our study found that current practices that promote transparency and reproducibility are lacking, thus, there is room for improvement. In particular, investigators should pre-register studies prior to commencement. Researchers should also make the materials, data, and analysis script publicly available. Further, individuals should be transparent about funding sources for the project and financial conflicts of interest. Research stakeholders should work together toward improvements on these matters. With such protections, the field of addiction medicine can better disseminate the information necessary to treat patients.
KW - Addiction
KW - Evidence-based research
KW - Open access
KW - Replication
KW - Reproducibility
KW - Transparency
UR - http://www.scopus.com/inward/record.url?scp=85088921103&partnerID=8YFLogxK
U2 - 10.1016/j.addbeh.2020.106560
DO - 10.1016/j.addbeh.2020.106560
M3 - Review article
C2 - 32763621
AN - SCOPUS:85088921103
SN - 0306-4603
VL - 112
JO - Addictive Behaviors
JF - Addictive Behaviors
M1 - 106560
ER -