Amphibian model for developing and evaluating retinal prostheses

Warren E. Finn, Peter G. LoPresti

Research output: Contribution to journalConference articlepeer-review

Abstract

The current project seeks to address the problem of constructing models with which to guide the development and evaluation of retinal prosthesis designs. In particular, the efforts described in this paper are intended to develop a more complete understanding of how electrical stimulation of ganglion cells by external electrodes interacts with retinal surface tissues, and how specific stimuli are encoded by the retinal and optic nerve processing systems. Toward this end, novel surgical techniques, optic tectum recording from live animals, correlational analysis, and systematic electrophysiological recording of stimulation are utilized. Microsurgical methods for providing a repeatable, chronic implantation of a stimulating prostheses have been developed. An opto-electronic processor capable of reliably encoding wavelength-dependent intensity information, including sensitivity changes with light adaptation has also been constructed.

Original languageEnglish
Pages (from-to)1540-1541
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume4
StatePublished - 1996
EventProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 4 (of 5) - Amsterdam, Neth
Duration: 31 Oct 19963 Nov 1996

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