@article{2a8c8a158cf449689d4875d2e96ccb49,
title = "Always on my mind: Cross-brain associations of mental health symptoms during simultaneous parent-child scanning",
abstract = "How parents manifest symptoms of anxiety or depression may affect how children learn to modulate their own distress, thereby influencing the children's risk for developing an anxiety or mood disorder. Conversely, children's mental health symptoms may impact parents' experiences of negative emotions. Therefore, mental health symptoms can have bidirectional effects in parent-child relationships, particularly during moments of distress or frustration (e.g., when a parent or child makes a costly mistake). The present study used simultaneous functional magnetic resonance imaging (fMRI) of parent-adolescent dyads to examine how brain activity when responding to each other's costly errors (i.e., dyadic error processing) may be associated with symptoms of anxiety and depression. While undergoing simultaneous fMRI scans, healthy dyads completed a task involving feigned errors that indicated their family member made a costly mistake. Inter-brain, random-effects multivariate modeling revealed that parents who exhibited decreased medial prefrontal cortex and posterior cingulate cortex activation when viewing their child's costly error response had children with more symptoms of depression and anxiety. Adolescents with increased anterior insula activation when viewing a costly error made by their parent had more anxious parents. These results reveal cross-brain associations between mental health symptomatology and brain activity during parent-child dyadic error processing.",
keywords = "Adolescence, Anxiety, Depression, Error processing, Parent-child interactions, fMRI",
author = "Cosgrove, {Kelly T.} and Kerr, {Kara L.} and Aupperle, {Robin L.} and Ratliff, {Erin L.} and DeVille, {Danielle C.} and Silk, {Jennifer S.} and Kaiping Burrows and Moore, {Andrew J.} and Chase Antonacci and Masaya Misaki and Tapert, {Susan F.} and Jerzy Bodurka and Simmons, {W. Kyle} and Morris, {Amanda Sheffield}",
note = "Funding Information: RLA receives funding from the National Institute of Mental Health (K23MH108707) and (P20GM121312). JB receives funding from the National Institute of General Medical Sciences (P20GM121312). WKS is an employee of Janssen Research & Development, LLC., of Johnson & Johnson, and holds equity in Johnson & Johnson. WKS is an inventor of a patent regarding appetite change in depression. The remaining authors have no declarations of interest. Funding Information: This research was supported by a Centers of Biomedical Research Excellence grant ( P20GM199097 , PD: Jennifer Hays-Grudo; funded by the National Institutes of Health) and The William K. Warren Foundation. The funding sources were not involved in study design; in the collection, analysis, and interpretation of data; in the writing of the article; or in the decision to submit the article for publication. RLA receives funding from the National Institute of Mental Health (K23MH108707) and (P20GM121312). JB receives funding from the National Institute of General Medical Sciences (P20GM121312). WKS is an employee of Janssen Research & Development, LLC., of Johnson & Johnson, and holds equity in Johnson & Johnson. WKS is an inventor of a patent regarding appetite change in depression. The remaining authors have no declarations of interest. Publisher Copyright: {\textcopyright} 2019 The Authors",
year = "2019",
month = dec,
doi = "10.1016/j.dcn.2019.100729",
language = "English",
volume = "40",
journal = "Developmental Cognitive Neuroscience",
issn = "1878-9293",
publisher = "Elsevier BV",
}