Abstract
Objective: To examine recruitment and retention strategies, focusing on historically marginalized populations within laryngeal cancer clinical trials since 2018.
Methods: After identifying relevant laryngeal cancer trials from Embase (Elsevier) and MEDLINE (PubMed), a standardized Google Form was used to extract relevant article characteristics including mention of recruitment or retention strategies aimed at historically marginalized groups. Two of the authors carried out data extraction in a masked duplicate fashion. Trials meeting predefined inclusion criteria (i.e. publication after 2018, conducted in a country with an Ethnic Fractionalization Index (EFI) of ≥ 0.3, and with intervention for laryngeal cancer patients) were selected for our cross-sectional analysis.
Results: Of the 38 included trials, only 3 (7.9%) discussed implementing strategies to improve participant retention while none (0%) mentioned any recruitment strategies. Only two (5.3%) cited limitations related to recruitment with the most common being travel distance for participants.
Conclusion: Laryngeal cancer studies lacked reporting of diversity-focused recruitment strategies. Given the recognized need for diverse participation in cancer studies, more comprehensive implementation of these strategies is critical for improving outcomes and decreasing inequities among patients. Transparent discussion of enrollment methods by publications will establish broader generalizability in laryngeal cancer trials.
Methods: After identifying relevant laryngeal cancer trials from Embase (Elsevier) and MEDLINE (PubMed), a standardized Google Form was used to extract relevant article characteristics including mention of recruitment or retention strategies aimed at historically marginalized groups. Two of the authors carried out data extraction in a masked duplicate fashion. Trials meeting predefined inclusion criteria (i.e. publication after 2018, conducted in a country with an Ethnic Fractionalization Index (EFI) of ≥ 0.3, and with intervention for laryngeal cancer patients) were selected for our cross-sectional analysis.
Results: Of the 38 included trials, only 3 (7.9%) discussed implementing strategies to improve participant retention while none (0%) mentioned any recruitment strategies. Only two (5.3%) cited limitations related to recruitment with the most common being travel distance for participants.
Conclusion: Laryngeal cancer studies lacked reporting of diversity-focused recruitment strategies. Given the recognized need for diverse participation in cancer studies, more comprehensive implementation of these strategies is critical for improving outcomes and decreasing inequities among patients. Transparent discussion of enrollment methods by publications will establish broader generalizability in laryngeal cancer trials.
| Original language | American English |
|---|---|
| State | Published - 14 Feb 2025 |
| Event | Oklahoma State University Center for Health Sciences Research Week 2025 - Oklahoma State University Center for Health Sciences, Tulsa, United States Duration: 10 Feb 2025 → 14 Feb 2025 https://medicine.okstate.edu/research/research_days.html |
Conference
| Conference | Oklahoma State University Center for Health Sciences Research Week 2025 |
|---|---|
| Country/Territory | United States |
| City | Tulsa |
| Period | 10/02/25 → 14/02/25 |
| Internet address |
Keywords
- laryngeal cancer
- diversity
- cross-sectional study