Subhas Das, PhD

Visiting Assistant Professor

  • 226 Citations
  • 6 h-Index
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Personal profile

Research Interests

Chronic inflammatory pain is the hallmark of inflammatory bowel disease including Ulcerative Colitis and Crohn’s Disease. Glutaminase (GLS), the enzyme that converts glutamine to glutamate, the excitatory neurotransmitter in sensory neurons are at the center of glutamate metabolism and has been shown to be elevated in chronic inflammatory pain. We are interested in finding different epigenetic fingerprints, which are involved in regulating this enzyme to control chronic pain in rat model of colitis.

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  • 3 Similar Profiles
Narcotic Antagonists Medicine & Life Sciences
Opioid Analgesics Medicine & Life Sciences
Morphine Medicine & Life Sciences
Astrocytes Medicine & Life Sciences
Chemokine CXCL10 Medicine & Life Sciences
Phosphoric Triester Hydrolases Medicine & Life Sciences
mu Opioid Receptor Medicine & Life Sciences
Chemokines Medicine & Life Sciences

Research Output 2006 2015

  • 226 Citations
  • 6 h-Index
  • 6 Article
  • 1 Review article
8 Citations (Scopus)
Narcotic Antagonists
mu Opioid Receptor
31 Citations (Scopus)

Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a

Banerjee, S., Meng, J., Das, S., Krishnan, A., Haworth, J., Charboneau, R., Zeng, Y., Ramakrishnan, S. & Roy, S., 8 Jul 2013, In : Scientific Reports. 3, 1977.

Research output: Contribution to journalArticle

Open Access
Septic Shock
49 Citations (Scopus)

Pharmacological characterization of LPS and opioid interactions at the toll-like receptor 4

Stevens, C. W., Aravind, S., Das, S. & Davis, R. L., 1 Mar 2013, In : British Journal of Pharmacology. 168, 6, p. 1421-1429 9 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Opioid Analgesics
Narcotic Antagonists
3 Citations (Scopus)

β-Funaltrexamine inhibits chemokine (CXCL10) expression in normal human astrocytes

Davis, R. L., Das, S., Buck, D. J. & Stevens, C. W., 1 Mar 2013, In : Neurochemistry International. 62, 4, p. 478-485 8 p.

Research output: Contribution to journalArticle

Chemokine CXCL10
Narcotic Antagonists
13 Citations (Scopus)
Open Access
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1