Randy Wymore, PhD

Interim Associate Dean for Curriculum, Associate Professor of Pharmacology

  • 3110 Citations
  • 18 h-Index
19942008
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Research Output 1994 2008

  • 3110 Citations
  • 18 h-Index
  • 17 Article
  • 1 Review article
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Article
2008
40 Citations (Scopus)

Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells

Guasti, L., Crociani, O., Redaelli, E., Pillozzi, S., Polvani, S., Masselli, M., Mello, T., Galli, A., Amedei, A., Wymore, R. S., Wanke, E. & Arcangeli, A., 1 Aug 2008, In : Molecular and Cellular Biology. 28, 16, p. 5043-5060 18 p.

Research output: Contribution to journalArticle

Neoplasms
Protein Isoforms
Ion Channels
Ubiquitin
Neuroblastoma
2005
115 Citations (Scopus)

Human ether-a-go-go-related gene 1 channels are physically linked to β 1 integrins and modulate adhesion-dependent signaling

Cherubini, A., Hofmann, G., Pillozzi, S., Guasti, L., Crociani, O., Cilia, E., Di Stefano, P., Degani, S., Balzi, M., Olivotto, M., Wanke, E., Becchetti, A., Defilippi, P., Wymore, R. & Arcangeli, A., 9 Jun 2005, In : Molecular Biology of the Cell. 16, 6, p. 2972-2983 12 p.

Research output: Contribution to journalArticle

Integrins
Ether
Genes
Focal Adhesion Protein-Tyrosine Kinases
Proteins
2003
159 Citations (Scopus)

Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells

Crociani, O., Guasti, L., Balzi, M., Becchetti, A., Wanke, E., Olivotto, M., Wymore, R. S. & Arcangeli, A., 31 Jan 2003, In : Journal of Biological Chemistry. 278, 5, p. 2947-2955 9 p.

Research output: Contribution to journalArticle

Tumors
Cell Cycle
Protein Isoforms
Cells
Neoplasms
2002
98 Citations (Scopus)

Isoform-specific stimulation of cardiac Na/K pumps by nanomolar concentrations of glycosides

Gao, J., Wymore, R. S., Wang, Y., Gaudette, G. R., Krukenkamp, I. B., Cohen, I. S. & Mathias, R. T., 25 Apr 2002, In : Journal of General Physiology. 119, 4, p. 297-312 16 p.

Research output: Contribution to journalArticle

Glycosides
Protein Isoforms
Ouabain
Muscle Cells
Guinea Pigs
2001
200 Citations (Scopus)

MinK-related peptide 1: A beta subunit for the HCN ion channel subunit family enhances expression and speeds activation.

Yu, H., Wu, J., Potapova, I., Wymore, R. T., Holmes, B., Zuckerman, J., Pan, Z., Wang, H., Shi, W., Robinson, R. B., El-Maghrabi, M. R., Benjamin, W., Dixon, J., McKinnon, D., Cohen, I. S. & Wymore, R., 22 Jun 2001, In : Circulation Research. 88, 12, p. E84-87

Research output: Contribution to journalArticle

Mink
Ion Channels
Peptides
Nervous System
Proteins
2000
111 Citations (Scopus)

Effects of the renin-angiotensin system on the current I(to) in epicardial and endocardial ventricular myocytes from the canine heart

Yu, H., Gao, J., Wang, H., Wymore, R., Steinberg, S., McKinnon, D., Rosen, M. R. & Cohen, I. S., 26 May 2000, In : Circulation Research. 86, 10, p. 1062-1068 7 p.

Research output: Contribution to journalArticle

Renin-Angiotensin System
Endocardium
Angiotensin II
Muscle Cells
Canidae
52 Citations (Scopus)

Isoform-specific function and distribution of Na/K pumps in the frog lens epithelium

Gao, J., Sun, X., Yatsula, V., Wymore, R. S. & Mathias, R. T., 15 Nov 2000, In : Journal of Membrane Biology. 178, 2, p. 89-101 13 p.

Research output: Contribution to journalArticle

Anura
Lenses
Protein Isoforms
Epithelium
Ouabain
1999
299 Citations (Scopus)

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues.

Shi, W., Wymore, R., Yu, H., Wu, J., Wymore, R. T., Pan, Z., Robinson, R. B., Dixon, J. E., McKinnon, D. & Cohen, I. S., 9 Jul 1999, In : Circulation Research. 85, 1, p. e1-6

Research output: Contribution to journalArticle

Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Messenger RNA
Protein Isoforms
Rabbits
Purkinje Fibers
38 Citations (Scopus)

Isoform-specific regulation of the sodium pump by α- and β-adrenergic agonists in the guinea-pig ventricle

Gao, J., Wymore, R., Wymore, R. T., Wang, Y., McKinnon, D., Dixon, J. E., Mathias, R. T., Cohen, I. S. & Baldo, G. J., 15 Apr 1999, In : Journal of Physiology. 516, 2, p. 377-383 7 p.

Research output: Contribution to journalArticle

Sodium-Potassium-Exchanging ATPase
Adrenergic Agonists
Protein Isoforms
Guinea Pigs
Ribonucleases
115 Citations (Scopus)

Transient outward current, I(to1), is altered in cardiac memory

Yu, H., McKinnon, D., Dixon, J. E., Gao, J., Wymore, R., Cohen, I. S., Danilo, P., Shvilkin, A., Anyukhovsky, E. P., Sosunov, E. A., Hara, M. & Rosen, M. R., 13 Apr 1999, In : Circulation. 99, 14, p. 1898-1905 8 p.

Research output: Contribution to journalArticle

Long-Term Memory
Cardiac Myocytes
Action Potentials
Electrocardiography
Electrophysiology
1998
40 Citations (Scopus)

Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia

Shi, W., Wang, H. S., Pan, Z., Wymore, R. S., Cohen, I. S., McKinnon, D. & Dixon, J. E., 15 Sep 1998, In : Journal of Physiology. 511, 3, p. 675-682 8 p.

Research output: Contribution to journalArticle

Sympathetic Ganglia
Potassium Channels
Organism Cloning
Messenger RNA
Genes
878 Citations (Scopus)

KCNQ2 and KCNQ3 potassium channel subunits: Molecular correlates of the M-channel

Wang, H. S., Pan, Z., Shi, W., Brown, B. S., Wymore, R. S., Cohen, I. S., Dixon, J. E. & McKinnon, D., 4 Dec 1998, In : Science. 282, 5395, p. 1890-1893 4 p.

Research output: Contribution to journalArticle

KCNQ3 Potassium Channel
KCNQ2 Potassium Channel
Pharmacology
Neurons
Genes
1997
167 Citations (Scopus)

Identification of two nervous system-specific members of the erg potassium channel gene family

Shi, W., Wymore, R. S., Wang, H. S., Pan, Z., Cohen, I. S., McKinnon, D. & Dixon, J. E., 1 Dec 1997, In : Journal of Neuroscience. 17, 24, p. 9423-9432 10 p.

Research output: Contribution to journalArticle

Potassium Channels
Nervous System
Genes
Long QT Syndrome
Sympathetic Ganglia
144 Citations (Scopus)

Tissue and species distribution of mRNA for the I(kr)-like K+ channel, erg

Wymore, R., Gintant, G. A., Wymore, R. T., Dixon, J. E., McKinnon, D. & Cohen, I. S., 1 Jan 1997, In : Circulation Research. 80, 2, p. 261-268 8 p.

Research output: Contribution to journalArticle

Tissue Distribution
Messenger RNA
Long QT Syndrome
Ribonucleases
Adrenal Glands
1996
30 Citations (Scopus)

Characterization of the transcription unit of mouse Kv1.4, a voltage- gated potassium channel gene

Wymore, R. S., Negulescu, D., Kinoshita, K., Kalman, K., Aiyar, J., Gutman, G. A. & George Chandy, K., 16 Jul 1996, In : Journal of Biological Chemistry. 271, 26, p. 15629-15634 6 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Transcription
Genes
Messenger RNA
Exons
375 Citations (Scopus)

Role of the Kv4.3 K+ channel in ventricular muscle: A molecular correlate for the transient outward current

Dixon, J. E., Shi, W., Wang, H. S., McDonald, C., Yu, H., Wymore, R. S., Cohen, I. S. & McKinnon, D., 1 Jan 1996, In : Circulation Research. 79, 4, p. 659-668 10 p.

Research output: Contribution to journalArticle

Canidae
Muscles
Muscle Cells
Genes
Action Potentials
1994
30 Citations (Scopus)

Genomic organization, nucleotide sequence, biophysical properties, and localization of the voltage-gated K+ channel gene KCNA4/Kv1.4 to mouse chromosome 2/human 11p14 and mapping of KCNC1/Kv3.1 to mouse 7/human 11p14.3-p15.2 and KCNA1/Kv1.1 to human 12p13

Wymore, R. S., Korenberg, J. R., Kinoshita, K. D., Aiyar, J., Coyne, C., Chen, X. N., Hustad, C. M., Copeland, N. G., Gutman, G. A., Jenkins, N. A. & Chandy, K. G., 15 Mar 1994, In : Genomics. 20, 2, p. 191-202 12 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Chromosomes, Human, Pair 2
Genes
Exons
Shaker Superfamily of Potassium Channels