Randy Wymore, PhD

Interim Associate Dean for Curriculum, Associate Professor of Pharmacology

  • 3195 Citations
  • 18 h-Index
19942008

Research output per year

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Research Output

  • 3195 Citations
  • 18 h-Index
  • 17 Article
  • 1 Review article
2008

Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells

Guasti, L., Crociani, O., Redaelli, E., Pillozzi, S., Polvani, S., Masselli, M., Mello, T., Galli, A., Amedei, A., Wymore, R. S., Wanke, E. & Arcangeli, A., Aug 2008, In : Molecular and Cellular Biology. 28, 16, p. 5043-5060 18 p.

Research output: Contribution to journalArticle

43 Scopus citations
2005

Human ether-a-go-go-related gene 1 channels are physically linked to β 1 integrins and modulate adhesion-dependent signaling

Cherubini, A., Hofmann, G., Pillozzi, S., Guasti, L., Crociani, O., Cilia, E., Di Stefano, P., Degani, S., Balzi, M., Olivotto, M., Wanke, E., Becchetti, A., Defilippi, P., Wymore, R. & Arcangeli, A., 2005, In : Molecular Biology of the Cell. 16, 6, p. 2972-2983 12 p.

Research output: Contribution to journalArticle

120 Scopus citations
2003

Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells

Crociani, O., Guasti, L., Balzi, M., Becchetti, A., Wanke, E., Olivotto, M., Wymore, R. S. & Arcangeli, A., 31 Jan 2003, In : Journal of Biological Chemistry. 278, 5, p. 2947-2955 9 p.

Research output: Contribution to journalArticle

163 Scopus citations

International Union of Pharmacology. XLI. Compendium of Voltage-Gated Ion Channels: Potassium Channels

Gutman, G. A., Chandy, K. G., Adelman, J. P., Aiyar, J., Bayliss, D. A., Clapham, D. E., Covarriubias, M., Desir, G. V., Furuichi, K., Ganetzky, B., Garcia, M. L., Grissmer, S., Jan, L. Y., Karschin, A., Kim, D., Kuperschmidt, S., Kurachi, Y., Lazdunski, M., Lesage, F., Lester, H. A. & 14 others, McKinnon, D., Nichols, C. G., O'Kelly, I., Robbins, J., Robertson, G. A., Rudy, B., Sanguinetti, M., Seino, S., Stuehmer, W., Tamkun, M. M., Vandenberg, C. A., Wei, A., Wulff, H. & Wymore, R. S., Dec 2003, In : Pharmacological Reviews. 55, 4, p. 583-586 4 p.

Research output: Contribution to journalReview article

226 Scopus citations
2002

Isoform-specific stimulation of cardiac Na/K pumps by nanomolar concentrations of glycosides

Gao, J., Wymore, R. S., Wang, Y., Gaudette, G. R., Krukenkamp, I. B., Cohen, I. S. & Mathias, R. T., 2002, In : Journal of General Physiology. 119, 4, p. 297-312 16 p.

Research output: Contribution to journalArticle

100 Scopus citations
2001

MinK-related peptide 1: A beta subunit for the HCN ion channel subunit family enhances expression and speeds activation.

Yu, H., Wu, J., Potapova, I., Wymore, R. T., Holmes, B., Zuckerman, J., Pan, Z., Wang, H., Shi, W., Robinson, R. B., El-Maghrabi, M. R., Benjamin, W., Dixon, J., McKinnon, D., Cohen, I. S. & Wymore, R., 22 Jun 2001, In : Circulation Research. 88, 12, p. E84-87

Research output: Contribution to journalArticle

203 Scopus citations
2000

Effects of the renin-angiotensin system on the current I(to) in epicardial and endocardial ventricular myocytes from the canine heart

Yu, H., Gao, J., Wang, H., Wymore, R., Steinberg, S., McKinnon, D., Rosen, M. R. & Cohen, I. S., 26 May 2000, In : Circulation Research. 86, 10, p. 1062-1068 7 p.

Research output: Contribution to journalArticle

113 Scopus citations

Isoform-specific function and distribution of Na/K pumps in the frog lens epithelium

Gao, J., Sun, X., Yatsula, V., Wymore, R. S. & Mathias, R. T., 15 Nov 2000, In : Journal of Membrane Biology. 178, 2, p. 89-101 13 p.

Research output: Contribution to journalArticle

53 Scopus citations
1999

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues.

Shi, W., Wymore, R., Yu, H., Wu, J., Wymore, R. T., Pan, Z., Robinson, R. B., Dixon, J. E., McKinnon, D. & Cohen, I. S., 9 Jul 1999, In : Circulation Research. 85, 1, p. e1-6

Research output: Contribution to journalArticle

Open Access
306 Scopus citations

Isoform-specific regulation of the sodium pump by α- and β-adrenergic agonists in the guinea-pig ventricle

Gao, J., Wymore, R., Wymore, R. T., Wang, Y., McKinnon, D., Dixon, J. E., Mathias, R. T., Cohen, I. S. & Baldo, G. J., 15 Apr 1999, In : Journal of Physiology. 516, 2, p. 377-383 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Transient outward current, I(to1), is altered in cardiac memory

Yu, H., McKinnon, D., Dixon, J. E., Gao, J., Wymore, R., Cohen, I. S., Danilo, P., Shvilkin, A., Anyukhovsky, E. P., Sosunov, E. A., Hara, M. & Rosen, M. R., 13 Apr 1999, In : Circulation. 99, 14, p. 1898-1905 8 p.

Research output: Contribution to journalArticle

115 Scopus citations
1998

Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia

Shi, W., Wang, H. S., Pan, Z., Wymore, R. S., Cohen, I. S., McKinnon, D. & Dixon, J. E., 15 Sep 1998, In : Journal of Physiology. 511, 3, p. 675-682 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

KCNQ2 and KCNQ3 potassium channel subunits: Molecular correlates of the M-channel

Wang, H. S., Pan, Z., Shi, W., Brown, B. S., Wymore, R. S., Cohen, I. S., Dixon, J. E. & McKinnon, D., 4 Dec 1998, In : Science. 282, 5395, p. 1890-1893 4 p.

Research output: Contribution to journalArticle

917 Scopus citations
1997

Identification of two nervous system-specific members of the erg potassium channel gene family

Shi, W., Wymore, R. S., Wang, H. S., Pan, Z., Cohen, I. S., McKinnon, D. & Dixon, J. E., 1997, In : Journal of Neuroscience. 17, 24, p. 9423-9432 10 p.

Research output: Contribution to journalArticle

Open Access
169 Scopus citations

Tissue and species distribution of mRNA for the I(kr)-like K+ channel, erg

Wymore, R. S., Gintant, G. A., Wymore, R. T., Dixon, J. E., McKinnon, D. & Cohen, I. S., 1997, In : Circulation Research. 80, 2, p. 261-268 8 p.

Research output: Contribution to journalArticle

148 Scopus citations
1996

Characterization of the transcription unit of mouse Kv1.4, a voltage- gated potassium channel gene

Wymore, R. S., Negulescu, D., Kinoshita, K., Kalman, K., Aiyar, J., Gutman, G. A. & George Chandy, K., 1996, In : Journal of Biological Chemistry. 271, 26, p. 15629-15634 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Role of the Kv4.3 K+ channel in ventricular muscle: A molecular correlate for the transient outward current

Dixon, J. E., Shi, W., Wang, H. S., McDonald, C., Yu, H., Wymore, R. S., Cohen, I. S. & McKinnon, D., 1996, In : Circulation Research. 79, 4, p. 659-668 10 p.

Research output: Contribution to journalArticle

380 Scopus citations
1994

Genomic organization, nucleotide sequence, biophysical properties, and localization of the voltage-gated K+ channel gene KCNA4/Kv1.4 to mouse chromosome 2/human 11p14 and mapping of KCNC1/Kv3.1 to mouse 7/human 11p14.3-p15.2 and KCNA1/Kv1.1 to human 12p13

Wymore, R. S., Korenberg, J. R., Kinoshita, K. D., Aiyar, J., Coyne, C., Chen, X. N., Hustad, C. M., Copeland, N. G., Gutman, G. A., Jenkins, N. A. & Chandy, K. G., 15 Mar 1994, In : Genomics. 20, 2, p. 191-202 12 p.

Research output: Contribution to journalArticle

30 Scopus citations