Keyphrases
Tissue-specific Knockout
100%
Complementary DNA (cDNA)
100%
Cas9 Protein
100%
Ataxia
90%
Exon Junction
90%
Biallelic Variants
90%
Single Guide RNA (sgRNA)
90%
Visual Impairment
90%
2-oxoglutarate Dehydrogenase
90%
Neurodevelopmental
90%
Drosophila Melanogaster
90%
Epilepsy
90%
Hearing Impairment
90%
Drosophilidae
80%
Pathogenicity
39%
Disease Variants
29%
Genomic Loci
29%
Guide RNA (gRNA)
29%
Gal4-UAS
29%
Human Genes
29%
Gal4
29%
MiRNA Target
29%
Krebs Cycle
19%
Synonymous Variant
19%
Mitochondrial Metabolism
19%
Lethality
19%
Corpus Callosum Dysgenesis
9%
Hypomorphic mutation
9%
Neurological Phenotype
9%
Compound Heterozygous mutation
9%
Gait Ataxia
9%
Behavioral Defects
9%
Frameshift Variant
9%
Gain-of-function mutation
9%
Exon 11
9%
Microcephaly
9%
Missense Variants
9%
Neurodevelopmental Phenotypes
9%
Rescue System
9%
Human Neuronal Cells
9%
Single nucleotide Variant
9%
Rate-limiting Enzyme
9%
Neurodevelopmental Disorders
9%
Metabolism
9%
Mitochondrial Respiration
9%
Fibroblasts
9%
Pan-neuronal
9%
Orthologs
9%
Transcriptome Analysis
9%
Biochemistry, Genetics and Molecular Biology
CRISPR/Cas9
100%
Exon
100%
Drosophila Melanogaster
90%
Oxidoreductase
90%
Dehydrogenase
90%
Intron
90%
Cas9
45%
Transgene
45%
Guide RNA
45%
Drive
45%
Genomics
45%
Mitochondrial Respiration
29%
Krebs Cycle
19%
Citric Acid Cycle
19%
Allele
19%
Missense
9%
Enzyme
9%
Single-Nucleotide Polymorphism
9%
Wild Type
9%
Orthology
9%
Metabolic Pathway
9%
Fibroblast
9%
Neuroscience
Ataxia
90%
Oxoglutarate Dehydrogenase
90%
Mitochondrial Respiration
29%
Citric Acid Cycle
19%
Microcephaly
9%
Corpus Callosum
9%
CRISPR
9%
Exon
9%
Metabolic Pathway
9%
Single-Nucleotide Polymorphism
9%
Complementary DNA
9%
Fibroblast
9%
