Hugo Arias, PhD

Clinical Professor of Pharmacology

  • 2756 Citations
  • 28 h-Index
1987 …2019
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Fingerprint Dive into the research topics where Hugo Arias is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Nicotinic Receptors Medicine & Life Sciences
Cholinergic Receptors Medicine & Life Sciences
Binding Sites Medicine & Life Sciences
Ion Channels Medicine & Life Sciences
Torpedo Medicine & Life Sciences
Bupropion Medicine & Life Sciences
Quinacrine Medicine & Life Sciences
Acrylamide Medicine & Life Sciences

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Research Output 1987 2019

3-Furan-2-yl-N-p-tolyl-acrylamide, a highly selective positive allosteric modulator of α7 nicotinic receptors, produces anxiolytic-like activity in mice

Targowska-Duda, K. M., Budzynska, B., Michalak, A., Jozwiak, K., Biala, G. & Arias, H. R., 1 May 2019, In : Journal of Psychopharmacology. 33, 5, p. 558-567 10 p.

Research output: Contribution to journalArticle

Anti-Anxiety Agents
Nicotinic Receptors

Alkaloids Purified from Aristotelia chilensis Inhibit the Human α3β4 Nicotinic Acetylcholine Receptor with Higher Potencies Compared with the Human α4β2 and α7 Subtypes

Arias, H. R., Ortells, M. O., Feuerbach, D., Burgos, V. & Paz, C., 1 Jan 2019, In : Journal of Natural Products. 82, 7, p. 1953-1960 8 p.

Research output: Contribution to journalArticle

Nicotinic Receptors
Cholinergic Receptors
Structure-Activity Relationship
Molecular Structure
2 Citations (Scopus)

Molecular interactions of type I and type II positive allosteric modulators with the human α7 nicotinic acetylcholine receptor: an in silico study

Targowska-Duda, K. M., Kaczor, A. A., Jozwiak, K. & Arias, H. R., 22 Jan 2019, In : Journal of Biomolecular Structure and Dynamics. 37, 2, p. 411-439 29 p.

Research output: Contribution to journalArticle

Nicotinic Receptors
Computer Simulation
Molecular Dynamics Simulation
Binding Sites

Selectivity of (±)-citalopram at nicotinic acetylcholine receptors and different inhibitory mechanisms between habenular α3β4* and α9α10 subtypes

Arias, H. R., Jin, X. T., Gallino, S., Peng, C., Feuerbach, D., García-Colunga, J., Elgoyhen, A. B., Drenan, R. M. & Ortells, M. O., 1 Dec 2019, In : Neurochemistry International. 131, 104552.

Research output: Contribution to journalArticle

Nicotinic Receptors
Cholinergic Receptors
Ion Channels
2 Citations (Scopus)
Nicotinic Receptors
Liver Mitochondrion
Cytochromes c
Calcium-Calmodulin-Dependent Protein Kinases