Gerwald Koehler, PhD

Professor of Microbiology, Professor of Microbiology

  • 1286 Citations
  • 18 h-Index
1991 …2020
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Research Output 1991 2020

2020

Intestinal microbiome and metal toxicity

Assefa, S. & Köhler, G., Feb 2020, In : Current Opinion in Toxicology. 19, p. 21-27 7 p.

Research output: Contribution to journalReview article

Microbiota
Toxicity
Metals
Health
Environmental Pollutants
2018
2 Citations (Scopus)

Fecal microbiota in the female prairie vole (Microtus ochrogaster)

Curtis, J. T., Assefa, S., Francis, A. & Köhler, G. A., Mar 2018, In : PLoS ONE. 13, 3, e0190648.

Research output: Contribution to journalArticle

Microtus ochrogaster
Arvicolinae
Microbiota
Brain
Nutrition

Postnatal maturation of the intestinal epithelial barrier in prairie voles

Supeck, D. J., Assefa, S., Meek, W., Curtis, T. & Koehler, G., 1 Oct 2018, In : Tissue and Cell. 54, p. 30-37 8 p.

Research output: Contribution to journalArticle

Arvicolinae
Tight Junctions
Permeability
Tight Junction Proteins
Premature Mortality
2016
8 Citations (Scopus)

In vitro analysis of Mg scaffolds coated with polymer/hydrogel/ceramic composite layers

Yazdimamaghani, M., Razavi, M., Vashaee, D., Pothineni, V. R., Assefa, S., Köhler, G. A., Rajadas, J. & Tayebi, L., 15 Sep 2016, In : Surface and Coatings Technology. 301, p. 126-132 7 p.

Research output: Contribution to journalArticle

Hydrogel
Hydrogels
Scaffolds
Magnesium
magnesium
2015
7 Citations (Scopus)

Candida albicans mutant construction and characterization of selected virulence determinants

Motaung, T. E., Albertyn, J., Pohl, C. H. & Köhler, G., 1 Jan 2015, In : Journal of Microbiological Methods. 115, p. 153-165 13 p.

Research output: Contribution to journalReview article

Candida albicans
Virulence
Yeasts
Virulence Factors
Gene Order
5 Citations (Scopus)

Lactobacilli with probiotic potential in the prairie vole (Microtus ochrogaster)

Assefa, S., Ahles, K., Bigelow, S., Curtis, T. & Koehler, G., 30 Dec 2015, In : Gut Pathogens. 7, 1, 35.

Research output: Contribution to journalArticle

Arvicolinae
Probiotics
Lactobacillus
Mercury
Intestines
4 Citations (Scopus)

Probiotics research in galleria mellonella

Köhler, G., 5 Feb 2015, In : Virulence. 6, 1, p. 3-5 3 p.

Research output: Contribution to journalEditorial

Lactobacillus acidophilus
Moths
Probiotics
Lactobacillus
Candida albicans
2014
30 Citations (Scopus)

Green synthesis of a new gelatin-based antimicrobial scaffold for tissue engineering

Yazdimamaghani, M., Vashaee, D., Assefa, S., Shabrangharehdasht, M., Rad, A. T., Eastman, M. A., Walker, K. J., Madihally, S. V., Köhler, G. A. & Tayebi, L., 1 Jun 2014, In : Materials Science and Engineering C. 39, 1, p. 235-244 10 p.

Research output: Contribution to journalArticle

tissue engineering
gelatins
Gelatin
Scaffolds (biology)
Tissue engineering
80 Citations (Scopus)

Hybrid macroporous gelatin/bioactive-glass/nanosilver scaffolds with controlled degradation behavior and antimicrobial activity for bone tissue engineering

Yazdimamaghani, M., Vashaee, D., Assefa, S., Walker, K. J., Madihally, S. V., Köhler, G. A. & Tayebi, L., Jun 2014, In : Journal of Biomedical Nanotechnology. 10, 6, p. 911-931 21 p.

Research output: Contribution to journalArticle

Bioactive glass
Gelatin
Tissue Engineering
Tissue engineering
Scaffolds
25 Citations (Scopus)

The effect of hyaluronic acid on biofunctionality of gelatin-collagen intestine tissue engineering scaffolds

Shabafrooz, V., Mozafari, M., Koehler, G., Assefa, S., Vashaee, D. & Tayebi, L., 1 Jan 2014, In : Journal of Biomedical Materials Research - Part A. 102, 9, p. 3130-3139 10 p.

Research output: Contribution to journalArticle

Tissue Scaffolds
Hyaluronic acid
Hyaluronic Acid
Gelatin
Scaffolds (biology)
2013
1 Citation (Scopus)

Genomics, microbiomes, single cell analysis and next-generation sequencing

Koehler, G. & Lau, P. C. K., 1 Jan 2013, In : Journal of Microbiological Methods. 95, 3, 1 p.

Research output: Contribution to journalArticle

Microbiological Techniques
Single-Cell Analysis
Microbiota
Genomics
2012
70 Citations (Scopus)
Lactobacillus reuteri
Lactobacillus rhamnosus
Vulvovaginal Candidiasis
Probiotics
Candida albicans
2011
2 Citations (Scopus)

Evaluation of the microbial flora found in woodwind and brass instruments and their potential to transmit diseases

Glass, R. T., Conrad, R. S., Kohler, G. A. & Bullard, J. W., 1 Mar 2011, In : General Dentistry. 59, 2, p. 100-107 8 p.

Research output: Contribution to journalArticle

Mouth
Students
Equipment and Supplies
Infectious Disease Transmission
Sanitation
11 Citations (Scopus)

Microbiota found in protective athletic mouthguards

Glass, R. T., Conrad, R. S., Köhler, G. A., Warren, A. J. & Bullard, J. W., 1 May 2011, In : Sports Health. 3, 3, p. 244-248 5 p.

Research output: Contribution to journalArticle

Microbiota
Sports
Bacillus
Gram-Positive Cocci
Fungi
2009
8 Citations (Scopus)

Protective athletic mouthguards: Do they cause harm?

Glass, R. T., Conrad, R. S., Wood, C. R., Warren, A. J., Kohler, G. A., Bullard, J. W., Benson, G. & Gulden, J. M., 1 Sep 2009, In : Sports Health. 1, 5, p. 411-415 5 p.

Research output: Contribution to journalArticle

Sports
Oral Diagnosis
Palate
Mouth Mucosa
Gingiva
24 Citations (Scopus)
Methionine
Cysteine
Anti-Inflammatory Agents
Leukocyte L1 Antigen Complex
Mutant Proteins
2006

Genomics of Pathogenic Fungi

Koehler, G., Kuo, A., Newport, G. & Agabian, N., 10 May 2006, Pathogenomics: Genome Analysis of Pathogenic Microbes. John Wiley and Sons, p. 389-416 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genomics
Mutagenesis
Fungi
54 Citations (Scopus)

Inactivation of the phospholipase B gene PLB5 in wild-type Candida albicans reduces cell-associated phospholipase A2 activity and attenuates virulence

Theiss, S., Ishdorj, G., Brenot, A., Kretschmar, M., Lan, C. Y., Nichterlein, T., Hacker, J., Nigam, S., Agabian, N. & Köhler, G. A., 12 Oct 2006, In : International Journal of Medical Microbiology. 296, 6, p. 405-420 16 p.

Research output: Contribution to journalArticle

Lysophospholipase
Phospholipases
Phospholipases A2
Multigene Family
Candida albicans
50 Citations (Scopus)

Phospholipase A2 and Phospholipase B activities in fungi

Köhler, G. A., Brenot, A., Haas-Stapleton, E., Agabian, N., Deva, R. & Nigam, S., 1 Nov 2006, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1761, 11, p. 1391-1399 9 p.

Research output: Contribution to journalReview article

Lysophospholipase
Phospholipases A2
Fungi
Lipids
Cell Communication
58 Citations (Scopus)

Role of calcineurin in stress resistance, morphogenesis, and virulence of a Candida albicans wild-type strain

Bader, T., Schröppel, K., Bentink, S., Agabian, N., Köhler, G. & Morschhäuser, J., 1 Jul 2006, In : Infection and Immunity. 74, 7, p. 4366-4369 4 p.

Research output: Contribution to journalArticle

Calcineurin
Candida albicans
Morphogenesis
Virulence
Hyphae
58 Citations (Scopus)

Selecting, testing and understanding probiotic microorganisms

Reid, G., Kim, S. O. & Koehler, G., 1 Mar 2006, In : FEMS Immunology and Medical Microbiology. 46, 2, p. 149-157 9 p.

Research output: Contribution to journalShort survey

Probiotics
Microbiota
Health
Anti-Bacterial Agents
Bacteria
2005
221 Citations (Scopus)

A human-curated annotation of the Candida albicans genome

Braun, B. R., van het Hoog, M., d'Enfert, C., Martchenko, M., Dungan, J., Kuo, A., Inglis, D. O., Uhl, M. A., Hogues, H., Berriman, M., Lorenz, M., Levitin, A., Oberholzer, U., Bachewich, C., Harcus, D., Marcil, A., Dignard, D., Iouk, T., Zito, R., Frangeul, L. & 23 others, Tekaia, F., Rutherford, K., Wang, E., Munro, C. A., Bates, S., Gow, N. A., Hoyer, L. L., Köhler, G., Morschhäuser, J., Newport, G., Znaidi, S., Raymond, M., Turcotte, B., Sherlock, G., Costanzo, M., Ihmels, J., Berman, J., Sanglard, D., Agabian, N., Mitchell, A. P., Johnson, A. D., Whiteway, M. & Nantel, A., Jul 2005, In : PLoS Genetics. 1, 1, p. 36-57 22 p.

Research output: Contribution to journalArticle

Candida albicans
Fungal Genome
genome
Genome
gene
3 Citations (Scopus)

CARE-2 fingerprinting of Candida albicans isolates.

Morschhäuser, J., Staib, P. & Köhler, G., 2005, In : Methods in molecular medicine. 118, p. 27-34 8 p.

Research output: Contribution to journalArticle

Candida albicans
Drug Resistance
Fungal Drug Resistance
Nucleic Acid Hybridization
Molecular Typing
12 Citations (Scopus)

Targeted gene deletion in Candida albicans wild-type strains by MPAR flipping.

Morschhäuser, J., Staib, P. & Koehler, G., 1 Jan 2005, In : Methods in molecular medicine. 118, p. 35-44 10 p.

Research output: Contribution to journalArticle

Gene Deletion
Candida albicans
Drug Resistance
Genes
Recombinases
44 Citations (Scopus)

The functional basis of mycophenolic acid resistance in Candida albicans IMP dehydrogenase

Koehler, G., Gong, X., Bentink, S., Theiss, S., Pagani, G. M., Agabian, N. & Hedstrom, L., 25 Mar 2005, In : Journal of Biological Chemistry. 280, 12, p. 11295-11302 8 p.

Research output: Contribution to journalArticle

IMP Dehydrogenase
Acid resistance
Mycophenolic Acid
Candida
Candida albicans
2002
39 Citations (Scopus)

Functional analysis of a vacuolar ABC transporter in wild-type Candida albicans reveals its involvement in virulence

Theiss, S., Kretschmar, M., Nichterlein, T., Hof, H., Agabian, N., Hacker, J. & Koehler, G., 17 Jun 2002, In : Molecular Microbiology. 43, 3, p. 571-584 14 p.

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
Candida albicans
Virulence
Genes
Poisons
2 Citations (Scopus)

Genome structure of pathogenic fungi

Koehler, G., Morschhäuser, J. & Hacker, J., 3 Apr 2002, In : Current Topics in Microbiology and Immunology. 264 II, p. 149-166 18 p.

Research output: Contribution to journalReview article

Fungal Genome
Aspergillus
Candida
Saccharomyces cerevisiae
Fungi
5 Citations (Scopus)

New molecular methods to study gene functions in Candida infections

Theiß, S., Koehler, G., Kretschmar, M., Nichterlein, T. & Hacker, J., 30 Nov 2002, In : Mycoses. 45, 9-10, p. 345-350 6 p.

Research output: Contribution to journalReview article

candidiasis
Candida albicans
Candida
animal pathogenic fungi
Fungi
2000
69 Citations (Scopus)

Activation of the multiple drug resistance gene MDR1 in fluconazole- resistant, clinical Candida albicans strains is caused by mutations in a trans-regulatory factor

Wirsching, S., Michel, S., Köhler, G. & Morschhäuser, J., 1 Jan 2000, In : Journal of Bacteriology. 182, 2, p. 400-404 5 p.

Research output: Contribution to journalArticle

Fluconazole
Multiple Drug Resistance
Candida albicans
Mutation
Genes
22 Citations (Scopus)

A molecular genetic system for the pathogenic yeast Candida dubliniensis

Staib, P., Michel, S., Köhler, G. & Morschhäuser, J., 25 Jan 2000, In : Gene. 242, 1-2, p. 393-398 6 p.

Research output: Contribution to journalArticle

Candida albicans
Candida
Mycophenolic Acid
Molecular Biology
Yeasts
52 Citations (Scopus)

Evolution of microbial pathogens

Morschhäuser, J., Koehler, G., Ziebuhr, W., Blum-Oehler, G., Dobrindt, U. & Hacker, J., 29 May 2000, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 355, 1397, p. 695-704 10 p.

Research output: Contribution to journalArticle

Genomic Islands
Pathogens
pathogenicity islands
Gene transfer
Horizontal Gene Transfer
9 Citations (Scopus)

Expression of virulence genes in Candida albicans

Staib, P., Kretschmar, M., Nichterlein, T., Kõhler, G. & Morschhäuser, J., 1 Jan 2000, In : Advances in Experimental Medicine and Biology. 485, p. 167-176 10 p.

Research output: Contribution to journalArticle

Candida
Candidiasis
Candida albicans
Virulence
Genes
1999
10 Citations (Scopus)

Adharenz und invasion: Zwei pathogenitatsfaktoren bei pathogenen bakterien und pilzen

Translated title of the contribution: Adherence and invasion - Two pathogenicity factors in bacterial and fungal pathogensMüller, F. M. C., Morschhäuser, J., Köhler, G., Oelschlaeger, T. A., Zicbuhr, W. & Hacker, J., 1 Jan 1999, In : Mycoses, Supplement. 42, 1, p. 39-42 4 p.

Research output: Contribution to journalArticle

Azoles
adhesins
Virulence Factors
Point Mutation
Virulence
110 Citations (Scopus)

Host-induced, stage-specific virulence gene activation in Candida albicans during infection

Staib, P., Kretschmar, M., Nichterlein, T., Koehler, G., Michel, S., Hof, H., Hacker, J. & Morschhäuser, J., 29 May 1999, In : Molecular Microbiology. 32, 3, p. 533-546 14 p.

Research output: Contribution to journalArticle

Candida albicans
Transcriptional Activation
Virulence
Infection
Genes
1997
155 Citations (Scopus)

Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid

Köhler, G. A., White, T. C. & Agabian, N., 1 Jan 1997, In : Journal of Bacteriology. 179, 7, p. 2331-2338 8 p.

Research output: Contribution to journalArticle

IMP Dehydrogenase
Mycophenolic Acid
Candida albicans
Saccharomyces cerevisiae
Genes
1996
3 Citations (Scopus)

Gibt es pathogenitatsfaktoren bei Pilzen?

Translated title of the contribution: Are there pathogenicity factors in fungi?Morschhäuser, J., Köhler, G. & Hacker, J., 17 Aug 1996, In : Mycoses, Supplement. 39, 1, p. 51-54 4 p.

Research output: Contribution to journalArticle

Virulence Factors
Fungi
Bacteria
Cryptococcus neoformans
Aspergillus fumigatus
1992

The Application of Polymerase Chain Reaction for Studying the Phylogeny of Bacteria

Köhler, G., Ludwig, W. & Schleifer, K. H., 1992, PCR: Clinical Diagnostics and Research. Rolfs, A., Schuller, I., Finckh, U. & Weber-Rolfs, I. (eds.). Berlin Heidelberg: Springer Verlag, p. A56-A59 4 p. (Springer Laboratory).

Research output: Chapter in Book/Report/Conference proceedingChapter

1991
33 Citations (Scopus)

Differentiation of lactococci by rRNA gene restriction analysis

Koehler, G., Ludwig, W. & Heinz Schleifer, K., 1 Dec 1991, In : FEMS Microbiology Letters. 84, 3, p. 307-312 6 p.

Research output: Contribution to journalArticle

Lactococcus
rRNA Genes
rRNA Operon
Polynucleotides
Lactococcus lactis