David Wallace, PhD

Director for Integrative Neuroscience, Professor of Pharmacology

  • 1155 Citations
  • 22 h-Index
1989 …2019
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Research Output 1989 2019

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Article
2019
5 Citations (Scopus)

Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures

Hernandez, A. F., Buha, A., Constantin, C., Wallace, D. R., Sarigiannis, D., Neagu, M., Antonijevic, B., Hayes, A. W., Wilks, M. F. & Tsatsakis, A., 1 Oct 2019, In : Archives of Toxicology. 93, 10, p. 2741-2757 17 p.

Research output: Contribution to journalArticle

Open Access
Risk assessment
Toxicity
Technology
Computer Simulation
Research Personnel
10 Citations (Scopus)

Environmental cadmium exposure and pancreatic cancer: Evidence from case control, animal and in vitro studies

Djordjevic, V. R., Wallace, D. R., Schweitzer, A., Boricic, N., Knezevic, D., Matic, S., Grubor, N., Kerkez, M., Radenkovic, D., Bulat, Z., Antonijevic, B., Matovic, V. & Buha, A., Jul 2019, In : Environment International. 128, p. 353-361 9 p.

Research output: Contribution to journalArticle

Open Access
cancer
cadmium
animal
exposure
etiology
11 Citations (Scopus)

Potential interaction of cadmium chloride with pancreatic mitochondria: Implications for pancreatic cancer

Wallace, D. R., Spandidos, D. A., Tsatsakis, A., Schweitzer, A., Djordjevic, V. & Djordjevic, A. B., 1 Jan 2019, In : International Journal of Molecular Medicine. 44, 1, p. 145-156 12 p.

Research output: Contribution to journalArticle

Open Access
Cadmium Chloride
Pancreatic Neoplasms
Mitochondria
Cadmium
Cell Line
27 Citations (Scopus)

Toxic effect of acute cadmium and lead exposure in rat blood, liver, and kidney

Andjelkovic, M., Djordjevic, A. B., Antonijevic, E., Antonijevic, B., Stanic, M., Kotur-Stevuljevic, J., Spasojevic-Kalimanovska, V., Jovanovic, M., Boricic, N., Wallace, D. & Bulat, Z., 2 Jan 2019, In : International Journal of Environmental Research and Public Health. 16, 2, 274.

Research output: Contribution to journalArticle

Poisons
Cadmium
Metals
Kidney
Body Weight
2010
34 Citations (Scopus)

Chronic metals ingestion by prairie voles produces sex-specific deficits in social behavior: An animal model of autism

Curtis, T., Hood, A. N., Chen, Y., Cobb, G. P. & Wallace, D., 1 Nov 2010, In : Behavioural Brain Research. 213, 1, p. 42-49 8 p.

Research output: Contribution to journalArticle

Arvicolinae
Social Behavior
Autistic Disorder
Animal Models
Eating
2009
59 Citations (Scopus)
tat Gene Products
Corpus Striatum
Synaptosomes
HIV-1
Dopamine
2006
25 Citations (Scopus)

Delta opioid agonists attenuate TAT1-72-induced oxidative stress in SK-N-SH cells

Wallace, D. R., Dodson, S. L., Nath, A. & Booze, R. M., 1 Jan 2006, In : NeuroToxicology. 27, 1, p. 101-107 7 p.

Research output: Contribution to journalArticle

naltrindole
Oxidative stress
Opioid Analgesics
D-Penicillamine (2,5)-Enkephalin
Oxidative Stress
75 Citations (Scopus)

Estrogen attenuates gp120- and tat1-72-induced oxidative stress and prevents loss of dopamine transporter function

Wallace, D. R., Dodson, S., Nath, A. & Booze, R. M., 1 Jan 2006, In : Synapse. 59, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

Dopamine Plasma Membrane Transport Proteins
Estrogens
Oxidative Stress
Synaptosomes
Corpus Striatum
15 Citations (Scopus)

Prenatal cocaine alters dopamine and sigma receptor binding in nucleus accumbens and striatum in dams and adolescent offspring

Silvers, J. M., Wallace, D. R., Harrod, S. B., Mactutus, C. F. & Booze, R. M., 1 Mar 2006, In : Neurotoxicology and Teratology. 28, 2, p. 173-180 8 p.

Research output: Contribution to journalArticle

sigma Receptors
Dopamine Receptors
Nucleus Accumbens
Cocaine
Dams
14 Citations (Scopus)

Prenatal cocaine exposure alters alpha2 receptor expression in adolescent rats

Booze, R. M., Wallace, D., Silvers, J. M., Strupp, B. J., Snow, D. M. & Mactutus, C. F., 18 Apr 2006, In : BMC Neuroscience. 7, 33.

Research output: Contribution to journalArticle

Cocaine
Adrenergic Receptors
Norepinephrine
Prosencephalon
Parietal Lobe
2004
32 Citations (Scopus)

New Geranyl Stilbenes from Dalea purpurea with in Vitro Opioid Receptor Affinity

Belofsky, G., French, A. N., Wallace, D. & Dodson, S. L., 1 Jan 2004, In : Journal of Natural Products. 67, 1, p. 26-30 5 p.

Research output: Contribution to journalArticle

Dalea purpurea
Stilbenes
stilbenes
narcotics
Opioid Receptors
2002
36 Citations (Scopus)

Characterization of μ, κ, and δ opioid binding in amphibian whole brain tissue homogenates

Newman, L. C., Sands, S. S., Wallace, D. R. & Stevens, C. W., 6 Apr 2002, In : Journal of Pharmacology and Experimental Therapeutics. 301, 1, p. 364-370 7 p.

Research output: Contribution to journalArticle

Amphibians
Opioid Analgesics
Brain
Opioid Receptors
D-Penicillamine (2,5)-Enkephalin
2000
22 Citations (Scopus)

Selective opioid agonist and antagonist competition for [3H]-naloxone binding in amphibian spinal cord

Newman, L. C., Wallace, D. R. & Stevens, C. W., 24 Nov 2000, In : Brain Research. 884, 1-2, p. 184-191 8 p.

Research output: Contribution to journalArticle

Narcotic Antagonists
Amphibians
Naloxone
Opioid Analgesics
Spinal Cord
19 Citations (Scopus)

Selective opioid receptor agonist and antagonist displacement of [3H]naloxone binding in amphibian brain

Newman, L. C., Wallace, D. R. & Stevens, C. W., 2 Jun 2000, In : European Journal of Pharmacology. 397, 2-3, p. 255-262 8 p.

Research output: Contribution to journalArticle

Narcotic Antagonists
Opioid Receptors
Amphibians
Naloxone
Rana pipiens
9 Citations (Scopus)

Sigma binding sites identified by [3H] DTG are elevated in aged Fischer-344 x brown Norway (F1) rats

Wallace, D. R., Mactutus, C. F. & Booze, R. M., 23 Feb 2000, In : Synapse. 35, 4, p. 311-313 3 p.

Research output: Contribution to journalArticle

Guanidines
Inbred BN Rats
sigma Receptors
Raclopride
Corpus Striatum
1999
9 Citations (Scopus)
Diprenorphine
Rana pipiens
Naltrexone
Naloxone
Tissue
33 Citations (Scopus)

L-type calcium channels in the hippocampus and cerebellum of Alzheimer's disease brain tissue

Coon, A. L., Wallace, D., MacTutus, C. F. & Booze, R. M., 1 Nov 1999, In : Neurobiology of Aging. 20, 6, p. 597-603 7 p.

Research output: Contribution to journalArticle

Cerebellar Diseases
L-Type Calcium Channels
Hippocampus
Alzheimer Disease
Brain
1998
5 Citations (Scopus)

[3H](+)-7-OH-DPAT and [3H]pramipexole binding in the striatum and nucleus accumbens of Sprague-Dawley and Fischer-344 rats

Wallace, D. R., Owens, J. & Booze, R. M., 2 Oct 1998, In : Life Sciences. 63, 19, p. PL275-PL280

Research output: Contribution to journalArticle

Inbred F344 Rats
Nucleus Accumbens
Rats
Corpus Striatum
Animals
7 Citations (Scopus)

Treatment of rat brain membranes with taurine increases radioligand binding

Green, P., Dawson, R., Wallace, D. R. & Owens, J., 1 Dec 1998, In : Advances in Experimental Medicine and Biology. 442, p. 377-383 7 p.

Research output: Contribution to journalArticle

Tetrahydronaphthalenes
Adrenergic alpha-Agonists
Excitatory Amino Acid Antagonists
Radioligand Assay
Dizocilpine Maleate
1997
94 Citations (Scopus)

Dose-response cocaine pharmacokinetics and metabolite profile following intravenous administration and arterial sampling in unanesthetized, freely moving male rats

Booze, R. M., Lehner, A. F., Wallace, D. R., Welch, M. A. & Mactutus, C. F., 1 Jan 1997, In : Neurotoxicology and Teratology. 19, 1, p. 7-15 9 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Metabolites
Cocaine
Intravenous Administration
Rats
32 Citations (Scopus)

Long-term treatment of male F344 rats with deprenyl: Assessment of effects on longevity, behavior, and brain function

Bickford, P. C., Adams, C. E., Boyson, S. J., Curella, P., Gerhardt, G. A., Heron, C., Ivy, G. O., Lin, A. M. L. Y., Murphy, M. P., Poth, K., Wallace, D., Young, D. A., Zahniser, N. R. & Rose, G. M., 1 Jan 1997, In : Neurobiology of Aging. 18, 3, p. 309-318 10 p.

Research output: Contribution to journalArticle

Selegiline
Inbred F344 Rats
Adrenergic Receptors
Brain
Monoamine Oxidase
4 Citations (Scopus)
Guanylyl Imidodiphosphate
Nitric Oxide
Up-Regulation
Nucleus Accumbens
Dopamine D3 Receptors
1996
8 Citations (Scopus)

Dopamine D3 receptor density elevation in aged Fischer-344 x Brown-Norway (F1) rats

Wallace, D. R. & Booze, R. M., 25 Jul 1996, In : European Journal of Pharmacology. 308, 3, p. 283-285 3 p.

Research output: Contribution to journalArticle

Dopamine D3 Receptors
Nucleus Accumbens
Guanylyl Imidodiphosphate
Corpus Striatum
Norway
50 Citations (Scopus)

Repeated intravenous cocaine administration: Locomotor activity and dopamine D2/D3 receptors

Wallace, D. R., Mactutus, C. F. & Booze, R. M., 1 Jul 1996, In : Synapse. 23, 3, p. 152-163 12 p.

Research output: Contribution to journalArticle

Dopamine D3 Receptors
Dopamine D2 Receptors
Locomotion
Cocaine
Intravenous Administration
1995
46 Citations (Scopus)

Dopamine D2 and D3 receptors in the rat striatum and nucleus accumbens: Use of 7-OH-DPAT and [125I]-iodosulpride

Booze, R. M. & Wallace, D., 14 Mar 1995, In : Synapse. 19, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Dopamine D3 Receptors
Dopamine D2 Receptors
Nucleus Accumbens
Dopamine Receptors
Islands of Calleja
39 Citations (Scopus)
Nucleus Accumbens
Rats
Corpus Striatum
Dopamine D3 Receptors
Ligands
3 Citations (Scopus)

Pramipexole: A dopamine D3-preferring compound that lacks interactions with sigma binding sites

Wallace, D. & Booze, R. M., 1 Jan 1995, In : Neuroscience Research Communications. 17, 3, p. 177-183 7 p.

Research output: Contribution to journalArticle

Dopamine
Binding Sites
Nucleus Accumbens
sigma Receptors
Guanidine
1994
1 Citation (Scopus)

Assessment of regional phosphate-activated glutaminase (PAG) activity and kinetics in adult and aged Fischer-344 rats

Wallace, D. R. & Dawson, R., 1 Apr 1994, In : AGE. 17, 2, p. 59-63 5 p.

Research output: Contribution to journalArticle

Glutaminase
Inbred F344 Rats
Temporal Lobe
Hippocampus
Phosphates
24 Citations (Scopus)
Idazoxan
Adrenergic Receptors
Pharmacology
Membranes
Glycylglycine
1993
10 Citations (Scopus)
Glutaminase
Temporal Lobe
Isoenzymes
Rats
Hippocampus
8 Citations (Scopus)

Regulation of phosphate-activated glutaminase (PAG) by glutamate analogues

Dawson, R. & Wallace, D. R., 1 Feb 1993, In : Neurochemical Research. 18, 2, p. 125-132 8 p.

Research output: Contribution to journalArticle

Glutaminase
Glutamic Acid
Taurine
Glutamine
Glycine
1992
14 Citations (Scopus)

Ammonia regulation of phosphate-activated glutaminase displays regional variation and impairment in the brain of aged rats

Wallace, D. R. & Dawson, R., 1 Nov 1992, In : Neurochemical Research. 17, 11, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Glutaminase
Ammonia
Rats
Brain
Ammonium Chloride
49 Citations (Scopus)

Kainic acid-induced scizures in aged rats: Neurochemical correlates

Dawson, R. & Wallace, D. R., 1 Jan 1992, In : Brain Research Bulletin. 29, 3-4, p. 459-468 10 p.

Research output: Contribution to journalArticle

Kainic Acid
Seizures
Norepinephrine
Long Evans Rats
Excitatory Amino Acids
25 Citations (Scopus)

Taurine content in tissues from aged Fischer 344 rats

Dawson, R. & Wallace, D. R., 1 Jul 1992, In : AGE. 15, 3, p. 73-81 9 p.

Research output: Contribution to journalArticle

Taurine
Inbred F344 Rats
Kidney
Glutamic Acid
Serum
1990
24 Citations (Scopus)

Decreased plasma taurine in aged rats

Wallace, D. R. & Dawson, R., 1 Jan 1990, In : Gerontology. 36, 1, p. 19-27 9 p.

Research output: Contribution to journalArticle

Taurine
Neurotransmitter Agents
Potassium
Brain
Blood Pressure
29 Citations (Scopus)
Sodium Glutamate
Inbred F344 Rats
Neurotransmitter Agents
Rats
Glutamic Acid
29 Citations (Scopus)

Excitatory amino acid involvement in retinal degeneration

Ulshafer, R. J., Sherry, D. M., Dawson, R. & Wallace, D., 29 Oct 1990, In : Brain Research. 531, 1-2, p. 350-354 5 p.

Research output: Contribution to journalArticle

Retinal Degeneration
Excitatory Amino Acids
Aspartic Acid
Retina
Glutamic Acid
16 Citations (Scopus)

Monoamine and amino acid content in brain regions of Brattleboro rats

Dawson, R., Wallace, D. R. & King, M. J., 1 Jul 1990, In : Neurochemical Research. 15, 7, p. 755-761 7 p.

Research output: Contribution to journalArticle

Brattleboro Rats
Rats
Brain
Amino Acids
Anterior Hypothalamus
7 Citations (Scopus)

Neural-renal interactions in the hypertension induced by papillary necrosis: Role of dietary salt intake

Dawson, R. & Wallace, D. R., 1 Jan 1990, In : Pharmacology. 40, 1, p. 42-53 12 p.

Research output: Contribution to journalArticle

Necrosis
Salts
Hypertension
Kidney
Norepinephrine
1989
8 Citations (Scopus)

Age- and dose-dependent effects of neonatal monosodium glutamate (MSG) administration to female rats

Dawson, R., Simpkins, J. W. & Wallace, D. R., 1 Jan 1989, In : Neurotoxicology and Teratology. 11, 4, p. 331-337 7 p.

Research output: Contribution to journalArticle

Sodium Glutamate
Rats
Median Eminence
Dopamine
Hypothalamus
36 Citations (Scopus)

A pharmacological analysis of food intake regulation in rats treated neonatally with monosodium L-glutamate (MSG)

Dawson, R., Wallace, D. R. & Gabriel, S. M., Feb 1989, In : Pharmacology, Biochemistry and Behavior. 32, 2, p. 391-398 8 p.

Research output: Contribution to journalArticle

Appetite Regulation
Sodium Glutamate
Rats
Glutamic Acid
Pharmacology
13 Citations (Scopus)

Central and peripheral actions of alpha2-adrenergic agonists on renal function in Long-Evans and Brattleboro rats

Dawson, R. & Wallace, D., 1 Jan 1989, In : Pharmacology. 39, 4, p. 240-252 13 p.

Research output: Contribution to journalArticle

Adrenergic alpha-2 Receptor Agonists
Brattleboro Rats
Long Evans Rats
Adrenergic Agonists
Adrenergic Receptors
48 Citations (Scopus)

Endogenous glutamate release from frontal cortex of adult and aged rats

Dawson, R., Wallace, D. & Meldrum, M. J., 1 Jan 1989, In : Neurobiology of Aging. 10, 6, p. 665-668 4 p.

Research output: Contribution to journalArticle

Frontal Lobe
Glutamic Acid
Kainic Acid
Brain
Synaptic Transmission