David Wallace, PhD

Director for Integrative Neuroscience, Professor of Pharmacology

  • 1093 Citations
  • 20 h-Index
1989 …2019
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Personal profile

Research Interests

My work focuses on the impact of environmental toxicant mixtures on the development of cancer. We examine the effects of heavy metals and pesticides on the cellular and molecular changes that occur following prolonged exposure to these toxicants and also how we may be able to prevent their cancer-causing effects.

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Rats Chemical Compounds
Nucleus Accumbens Medicine & Life Sciences
Inbred F344 Rats Medicine & Life Sciences
Brain Medicine & Life Sciences
Glutaminase Medicine & Life Sciences
Corpus Striatum Medicine & Life Sciences
Glutamic Acid Medicine & Life Sciences
Dopamine D3 Receptors Medicine & Life Sciences

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Research Output 1989 2019

Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures

Hernandez, A. F., Buha, A., Constantin, C., Wallace, D. R., Sarigiannis, D., Neagu, M., Antonijevic, B., Hayes, A. W., Wilks, M. F. & Tsatsakis, A., 1 Oct 2019, In : Archives of Toxicology. 93, 10, p. 2741-2757 17 p.

Research output: Contribution to journalArticle

Open Access
Risk assessment
Toxicity
Technology
Computer Simulation
Research Personnel
6 Citations (Scopus)

Environmental cadmium exposure and pancreatic cancer: Evidence from case control, animal and in vitro studies

Djordjevic, V. R., Wallace, D., Schweitzer, A., Boricic, N., Knezevic, D., Matic, S., Grubor, N., Kerkez, M., Radenkovic, D., Bulat, Z., Antonijevic, B., Matovic, V. & Buha, A., 1 Jul 2019, In : Environment International. 128, p. 353-361 9 p.

Research output: Contribution to journalArticle

Open Access
cancer
cadmium
animal
exposure
etiology
4 Citations (Scopus)

Potential interaction of cadmium chloride with pancreatic mitochondria: Implications for pancreatic cancer

Wallace, D., Spandidos, D. A., Tsatsakis, A., Schweitzer, A., Djordjevic, V. & Djordjevic, A. B., 1 Jan 2019, In : International Journal of Molecular Medicine. 44, 1, p. 145-156 12 p.

Research output: Contribution to journalArticle

Open Access
Cadmium Chloride
Pancreatic Neoplasms
Mitochondria
Cadmium
Cell Line
13 Citations (Scopus)

Toxic effect of acute cadmium and lead exposure in rat blood, liver, and kidney

Andjelkovic, M., Djordjevic, A. B., Antonijevic, E., Antonijevic, B., Stanic, M., Kotur-Stevuljevic, J., Spasojevic-Kalimanovska, V., Jovanovic, M., Boricic, N., Wallace, D. & Bulat, Z., 2 Jan 2019, In : International Journal of Environmental Research and Public Health. 16, 2, 274.

Research output: Contribution to journalArticle

Poisons
Cadmium
Metals
Kidney
Body Weight
19 Citations (Scopus)

Overview of cadmium thyroid disrupting effects and mechanisms

Buha, A., Matovic, V., Antonijevic, B., Bulat, Z., Curcic, M., Renieri, E. A., Tsatsakis, A. M., Schweitzer, A. & Wallace, D., 17 May 2018, In : International Journal of Molecular Sciences. 19, 5, 1501.

Research output: Contribution to journalReview article

disrupting
Cadmium
cadmium
Thyroid Gland
thyroid gland